CBD Is Giving Hope To Those With Parkinson’s Disease

There's a lot of information, analysis, and research swirling around regarding the relationship between CBD and Parkinson’s Disease. However, in this day and age, it’s increasingly difficult to parse fact from fiction when it comes to medical claims. It’s important that you always use a critical mind and a discerning eye when it comes to the sources you get your information from, especially when it comes to something like the brand new research surrounding CBD and Parkinson’s. Remember: if your research doesn’t contain links that verify claims with accurate empirical data, then the article might not be legitimate.

In this article, we will attempt to filter out the noise from the real information so that you can learn about the ever-evolving relationship between Parkinson's disease and CBD. We will provide empirical studies, analysis, and expert data that plainly lays out what we do and don’t know so far about research about CBD’s potential benefits for Parkinson’s sufferers.

Endocannabinoid System's Role In Parkinson's Disease's Treatment

The first essential thing you should learn more about in the modern treatment of Parkinson's Disease (PD) today is the role of cannabidiol (CBD). Scientists at University of Louisville School of Medicine have found a breakthrough discovery in the elements of CBD as a therapy for people with PD. The team ascertained that CBD can activate the G-coupled protein receptors in our body named "GPR6," which is expressed around our brain's basal ganglia region. GPR6 right now is named an "orphan receptor" primarily for the fact that researchers have not found yet the primary endogenous set of compounds that can effectively bind to this particular receptor.

A recent study from experts shows that a depletion of GPR6 will cause an increase in dopamine levels in the brain. Dopamine is one of the critical neurotransmitters of our body that can greatly affect the likelihood of experiencing Parkinson’s Disease. The analysis by the scientists has found that GPR6 may offer a robust treatment of Parkinson's, which is itself a neurodegenerative dysfunction that is mainly a result of low dopaminergic levels of neurons in our system -- which consequently causes an impairment of our body's motor movements. The GPR6 receptor can provide this aid to your body by simply boosting the dopamine levels in your system. Clinical studies show that this boost is significant enough to give the 10 million people who have Parkinson's disease today the hope of remedy. Parkinson’s Disease is the second most common disorder in the neurological system today, and with the help of GPR6, sufferers of this disease may soon have additional options to help them manage their ailments.

Lewy Bodies and Depletion of Dopamine Levels in Your Body Likely Cause Parkinson’s

A characteristic description of Parkinson’s Disease will usually talk about the compromised motor movements of the patient after suffering a significant reduction of one's dopamine-generating neurons. Over 60% of the dopamine of people with PD are reduced, damaged or rendered unusable. When this happens, the patient may experience some of these symptoms of dysfunctional motor functions: muscle rigidity, tremor of the hands, jaw, legs or arms, the stiffness of the limbs, trunk and slowness of movement (bradykinesia) and impaired gait, which also involves postural instability.

The brain with PD is filled with various and numerous “Lewy bodies” that are the main cause of the brain's dysfunction. These Lewy bodies are the intracellular aggregates of protein clusters in your body that your system finds hard to break down. When this difficulty occurs, a pathological disorder occurs, making the body with PD unable to think, have difficulty controlling behavior and mood, and motor functions that are hard to control. The hallmarks of PD today are mainly about having an excessive amounts of Lewy bodies in your system and a deteriorating level of dopaminergic neurons. These symptoms usually occur at the late stage of PD, when a majority of the dopamine-generating cells could no longer recover from significant damage.

This fact is the reason why it should be essential to diagnose Parkinson's disease at an early stage to lower the progression of the disease. Mounting evidence shows that if the symptoms of PD are addressed and won't be allowed to get the advanced-stage manifestations of the disease, the body may be able to fight the illness more effectively. PD is also determined by our body's evolving pathology, and this fact remains to be proof that addressing PD may still be more successful if the ailment is detected earlier.

Can Cannabinoid Acids Like CBDA Treat Parkinson’s Disease?

First off, we must make the distinction between anecdotal accounts, which vary from person to person and are not scientifically vetted, and peer-reviewed research. Yes, many anecdotal accounts exist that support the effectiveness of using certain CBD (and in some instances, THC) to help reduce tremors in the motor dysfunctions of people with Parkinson’s Disease. Some research shows that raw cannabinoid acids, such as THCA and CBDA, can have a significant level of therapeutic effects to lower some of the symptoms of PD; including nausea, inflammation, and seizures.

The bottom line is that, since CBD research surrounding treatment of Parkinson’s Disease is still in its infancy, you need to consult with your physician to determine whether it’s appropriate for you or your loved one who is suffering from PD to try CBD as part of a treatment plan.

Parkinson’s Disease Treatment

Understand that there is no cure for Parkinson's Disease, and nobody is purporting that CBD represents a cure -- especially in the near future. However, there are ways to hopefully prevent your body from succumbing to a PD diagnosis. Some of the tips listed by physicians that help avert PD include doing cardio aerobic exercise, eating more fruits and vegetables every day and doing meditation-based yoga. Getting frequent restful sleep will also provide a significant buffer for your body to prevent the onset of Parkinson's.

In the meantime, keep your eyes peeled for additional revelations that may result from research surrounding CBD and treating Parkinson’s Disease, and always remember to vet your sources wisely and consult with your physician before altering any treatment plan.

October 31, 2017 - CBDfx