One of the most common questions we get from customers is, “How long does it take to feel my CBD?” The answer is complicated, and it has to do with something called bioavailability. Bioavailability refers to the rate at which CBD is absorbed into your bloodstream, and the amount of CBD that is absorbed. But just what the bioavailability of CBD is for you, personally, depends on a variety of factors.
In this article, we’ll discuss all the factors that go into determining CBD bioavailability from CBD products and, hopefully, give you a better understanding of how CBD affects you.
What Is Bioavailability?
As we mentioned above, when we talk about bioavailability, we’re referring to the rate and amount of CBD entering your bloodstream. This is important to understand when you’re taking CBD, because it allows you to better anticipate when you might feel the effects of your CBD and determine your own ideal serving size.
Factors That Affect CBD Bioavailability
CBD, or cannabidiol, definitely isn’t a one-size-fits-all compound. Several different factors affect the absorption of CBD into the bloodstream, including all the things that make your body unique, as well as the amount of CBD you’re taking, the quality of the CBD, and the method of delivery. Let’s break down each of the factors that affect bioavailability.
CBD and Bioavailability: Understanding Your Body
You’re special! Every single one of you. Every single one of us! We all have different bodies, different physiologies. We all have a different combination of weight, height, body mass, and metabolism. Because we have such unique bodies, we all have a different tolerance to different chemicals or substances. And we can absorb chemical compounds, like the cannabinoid CBD, differently.
If you’re of drinking age, think about how differently a shot of tequila affects you versus the various people in your circle of friends. Or two shots, or three. Think about how many times you’ve heard someone say something to the effect of, “Ibuprofen doesn’t help me with headaches, but aspirin or acetaminophen does.”
In this same way, CBD can affect each of us differently, including bioavailability. That means, different people might need a different amount of CBD to feel the same effects. And it can mean the effects of CBD might kick in at a different rate. Understanding your own body is the first step to understanding the bioavailability of CBD for you.
CBD and Bioavailability: Quantity of CBD


Once you determine which CBD product you’re going to take, read the label to determine the strength of the product (usually marked by the milligrams of CBD) and the suggested serving size. Now, for your first dose, cut that serving size in half and see if that works. If it does, congratulations! Because of various bioavailability factors, your CBD product is going to last you twice as long. If it doesn’t work, when you try your CBD product again the next day, edge the amount up to, say, three-fourths of the suggested serving size and see if that works. Keep edging it up until you find the serving size that works for your body.

Also, take note that we suggested bumping up your serving size the next day — not an hour later after you didn’t feel any effects from the first dose. If you don’t wait for your first CBD dose to clear your system before taking more, you won’t know if you’re feeling the first dose kicking in later than expected or the extra serving. And you may, unintentionally, build up your tolerance by taking more CBD than you need.
CBD and Bioavailability: Purity of Your CBD Product
Two different CBD products, that tell you they have the same amount of CBD on the label, can actually have very different potency. When hemp-derived products became legal nationally after the 2018 Farm Bill was passed, there was a stampede of new brands that flooded the market with cheap, poor-quality CBD. This is why it’s so important to find a CBD brand whose products you can trust.

The purity of your CBD greatly affects the bioavailability of your product. If there’s less CBD and more filler in your product, you’re naturally going to absorb less CBD into your system. So, it’s always good to look for a CBD brand that uses organic, American-grown hemp and all-natural ingredients, as well as using a pure CO2 extraction process to remove the CBD oil from the hemp plant, leaving no residual solvent chemicals behind.
CBD and Bioavailability: Method of CBD Delivery
The way you take your CBD can have a huge impact on its bioavailability. CBD can be consumed in a number of ways, including sublingual, edible, vape, and topical consumption. The first three methods entail CBD being absorbed into your bloodstream. Topical CBD, on the other hand, is absorbed through the skin. But each of these four methods has its own nuances, which are important to understand if you want to know the bioavailability of your CBD product.
Sublingual CBD Products and Bioavailability

Sublingual CBD can also be absorbed at a much higher rate than CBD edibles. This is because CBD edibles, such as CBD gummies, have to pass through the digestive system and, in the process, lose some of their strength. CBD taken sublingually can have a bioavailability range of 15–35%. A good carrier oil, like natural coconut-derived MCT oil, helps the body to bump that number into the higher part of that range.

Edible CBD Products and Bioavailability
Edible CBD products are, you guessed it, CBD health supplements that are eaten. This group of CBD products passes through the digestive system before being absorbed into the bloodstream.
CBD edibles have the lowest bioavailability rate among delivery methods (5–15%). This is because the CBD loses some of its strength as it passes through the digestive system. But there are also benefits to consuming CBD as an edible. One of those benefits is that the CBD you do absorb stays in your system for a longer period of time, allowing you to experience its benefits longer. While it might take your CBD edible 20 minutes to two hours to kick in, you could potentially enjoy its effects all day or all night long.
CBD Vape Products and Bioavailability

It’s worth pointing out, on the topic of vaping, that our CBD vape products contain no nicotine and trace to undetectable levels of THC, and only use pure, organic broad spectrum CBD.
Topical CBD Products and Bioavailability
As we mentioned, CBD topicals are a bit different, because they’re not absorbed into the bloodstream at all. Instead, they’re generally rubbed into an affected area of the skin, offering localized relief for skin, muscles, joints, and deep tissues.**
The bioavailability rate of CBD topicals is quite high, compared to some other delivery methods, potentially reaching 45%.
The Last Word on CBD and Bioavailability

We hope that this article has helped you gain a better understanding of CBD and bioavailability, and we wish you all the best on your CBD wellness journey.
Looking to explore sublingual CBD? Explore our selection of organic CBD tincture oils!